产品货号：
Z25258
中文名称：
RHBDD3抗体
英文名称：
Anti-RHBDD3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RHBDD3 Antibody |
| 指标别名 | PTAG,C22orf3,HS984G1A,Rhomboid domain-containing protein 3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | RHBDD3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | RHBDD3 antibody was raised against a 13 amino acid synthetic peptide from near the center of human RHBDD3.The immunogen is located within amino acids 170 - 220 of RHBDD3. |
| 计算分子量 | 40kDa |
| 成分 | RHBDD3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | RHBDD3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development.RHBDD3 was initially identified as a novel pituitary tumor apoptosis gene (PTAG) whose expression was reduced in certain pituitary adenomas.Overexpression of RHBDD3 in AtT20 cells showed an increase in apoptotic activity and caspase activation in response to bromocriptine,and apoptosis-inducing dopamine D2 analog,suggesting that reactivation of RHBDD3 in tumors may be a therapeutically useful tool.Later experiments also showed that RHBDD3 expression is also reduced in several primary colorectal tumors,indicating that loss of RHBDD3 contributes to a blunted apoptotic response and probably predisposes cells towards malignant transformation. |
| Uniprot ID | Q9Y3P4 |
| 基因名全称 | Rhomboid domain containing 3 |
| 蛋白名全称 | Rhomboid domain containing 3 |
| 推荐稀释比 | RHBDD3 antibody can be used for detection of RHBDD3 by Western blot at 1μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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